Cellular Health · Powder Formula
Protocol 01
NR · Lion's Mane · CoQ10 · Resveratrol · 31 Actives
Contents: 30 single-serve sachets · 378g powder · 12.6g per serving · Coconut flavour
"NR is the most researched longevity compound of the last decade. The dosing in Protocol 01 is clinically meaningful and bioavailability-optimised."
Dr. Sarah Mitchell, PhD, Longevity & Cellular Biology
90-day supply · €198 billed every 3 months · all gifts day one
30 single-serve sachets per box, pre-portioned for exact dosing on the go.
Renews every 3 months · cancel any time.
Cancel anytime. No commitment required.
Pre-sale · Ships first week of January 2027
12.6g per serving · 30 servings · 378g total
Structural Foundation
- L-Creatine Monohydrate: 3000mg
- L-Glycine: 2000mg
- Trisodium Citrate: 1850mg
- Betaine Anhydrous: 1000mg
- Glucosamine Sulphate 2KCL: 1000mg
- Calcium Carbonate: 660mg
- Aquamin® Calcium Citrate Malate: 385mg
- Potassium Chloride: 380mg
Brain & Cognitive Health
- Lion's Mane Extract 5:1: 250mg
- Ginkgo Biloba Extract 10:1: 200mg
- Alpha Lipoic Acid: 200mg
Longevity & Cellular Health
- Japanese Knotweed Root Extract (100mg Resveratrol): 200mg
- Nicotinamide Riboside Chloride (NR): 200mg
- Sophora Japonica Extract (180.5mg Quercetin): 190mg
- Magnesium Malate: 185mg
- Magnesium Taurate: 107mg
- Coenzyme Q10: 100mg
- Sodium Hyaluronate (97mg Hyaluronic Acid): 100mg
- Astaxanthin Powder: 2.4mg
Vitamins & Minerals
- Vitamin B3 (Nicotinamide): 94.3mg · 589% NRV
- Vitamin C (L-Ascorbic Acid): 79.8mg · 100% NRV
- Zinc Bisglycinate: 37.5mg · 75% NRV
- Vitamin D3 (Cholecalciferol): 10mcg · 200% NRV
- Vitamin B7 (D-Biotin): 2mg · 80% NRV
- Vitamin B6 (Pyridoxine HCl): 1.4mg · 100% NRV
- Vitamin B1 (Thiamine HCl): 1.1mg · 100% NRV
- Chromium Picolinate: 240mcg · 60% NRV
- Vitamin B12 (Methylcobalamin): 200mcg · 80% NRV
- Vitamin K2 (MK-7): 52mcg · 69% NRV
- L-5-Methyltetrahydrofolate Calcium: 180mcg · 72% NRV
- Selenium (from Selenomethionine): 42mcg · 76% NRV
Tear open one sachet and mix with 200ml of cold water or juice. Take each morning, with or without food. Do not mix with hot liquids to preserve ingredient integrity.
NAD+ is essential for energy metabolism, DNA repair and sirtuin activation, proteins that regulate cellular ageing. NAD+ declines ~50% between ages 40 and 60. NR is its most bioavailable precursor, supported by multiple human clinical trials on healthy ageing.
- Free standard delivery on every order, UK and EU
- Pre-sale: every order ships in the first week of January 2027, with tracking by email
- Subscriptions pause or cancel in one click in your account
- 30-day money-back promise on your first order, even if opened
The Essense Promise
Feel it in 30 days, or it's on us.
Take Protocol 01 every morning for 30 days. If you don't feel the difference, tell us within 30 days of delivery and we refund your first order in full, even if the box is open. No forms, no questions.
- Full refund on your first order
- Even if opened
- One email is enough
Applies to the first order of Protocol 01 per customer. Refund to the original payment method.
The Philosophy
Engineered as one.
Most stacks are a shelf of single bottles fighting for attention. Protocol 01 was formulated as one system: each dose calibrated to work with the next, from NR and resveratrol to creatine and electrolytes.
The Ingredients
Full Label →How it works
One scoop vs a shelf of pills.
Rebuilding Protocol 01 from single products means four subscriptions, a cabinet of bottles and a handful of capsules every morning.
Typical UK retail for quality single-ingredient supplements, per month.
On the 3-Month Plan. £67/month on the monthly subscription, €92 one-time.
The Ritual
The morning decides the day.
200ml of cold water, one scoop, ten seconds. The simplest habit in your routine, and the one everything else builds on.
What to expect.
Longevity work compounds. Give it the 90 days it deserves.
Energy settles in
A steadier baseline replaces the caffeine rollercoaster: consistent energy through the afternoon and sharper focus in the morning.
Visible on the outside
Skin, hair and sleep quality typically respond next. The hyaluronic acid, biotin and mineral stack works quietly while the NAD+ pathway does the deep work.
Measurable change
Recovery, sleep and skin become noticeably different, and NAD+ level increases become measurable. This is why we recommend a 90-day commitment.
Individual results and timing vary.
Is it for you?
Food supplements are not a substitute for a varied, balanced diet and a healthy lifestyle.
What's in the box
Always included
30 Single-Serve Sachets
Pre-portioned for perfect dosing on the go, no scoops, no mess. Each box contains a 30-day supply.
Day one with the 3-month plan
Metal Jar
Brushed steel storage jar for your sachets. Engraved with the Essense mark, a ritual object built to last.
Month 1 with monthly · Day one with 3-month
Glass Water Bottle
500ml borosilicate glass with brushed steel cap. BPA-free, temperature-neutral, engraved with the Essense mark.
The ritual, daily.
Where Protocol 01 lives: the kitchen counter at 07:00, the shelf it cleared, and everywhere you take it.
Customer Reviews
312 verified reviews
Three months in and my energy is different. Not caffeine energy, a deep, consistent baseline. My partner noticed before I did.
I'm a functional medicine doctor. The stack is exactly what I'd formulate. Powder format means superior bioavailability. Genuinely impressive.
The scoop and bottle make this a proper ritual. I look forward to my morning mix every day. Four months with no intention of stopping.